Peter Kabos

This study shows that cfDNA can map telomere chromatin structure, revealing age-related and disease-specific changes in telomeric footprints and gene signatures.

This study shows estradiol suppresses microglial immunity and promotes breast cancer brain metastasis, with E2 suppression enhancing anti-tumor responses and synergizing with radiotherapy.

This study shows FGFR1 amplification drives ER+ breast cancer brain metastasis in young and aged mice via FGF2 and NCAM1 interactions, with FGFR inhibitors effective in early stages.

The paper shows that Maf1 and PR work together to reduce tRNA transcription in breast cancer cells under progestin treatment.

This study identifies lipid metabolic reprogramming in endocrine-resistant breast cancer cells, showing TVB-2640 reduces lipid storage but not cell growth.

This study investigates how metabolic changes in endocrine-resistant ER+ breast cancer cells affect ER DNA-binding patterns and shows that DMF can restore sensitivity to endocrine therapies by targeting metabolic vulnerabilities.

The paper shows that estradiol concentration changes the chromatin binding sites of the estrogen receptor, affecting its localization and interaction with DNA motifs.

This paper maps transcription factor-nucleosome dynamics from plasma cfDNA to identify cancer states and tissue-of-origin.

The paper develops a method to recover and analyze targeted transcriptome subsets from scRNA-seq libraries, improving sequencing depth and gene detection.