Antibiotic-Specific Conformational Landscapes of a Multidrug Transporter
Hassan Ramadan Mohamed Ahmed Maklad, Tom Kache, Aurélie Roth, Maria A. Mamkaeva, Cédric Govaerts, Jelle Hendrix, Chloé Martens
This study uses smFRET to analyze conformational dynamics of LmrP, revealing antibiotic-dependent heterogeneity in its conformational landscape and interconversion kinetics.
bioRxiv · May 17, 2025 · PreprintBiophysics