Nami Tajima

This study investigates how partial agonists affect desensitization in KARs, showing that agonist residence time and LBD closure are more critical than subunit composition in heteromeric receptors.

The paper determines cryo-EM structures of GluK2/GluK5 kainate receptors in apo and ligand-bound states, revealing conformational differences and subtype-specific antagonist effects.

This paper presents cryo-EM structures of kainate receptors showing conformational changes during desensitization and identifies structural differences from other iGluRs.