Fynn R. Eggersmann

This study shows that ROS-induced oxidation of gephyrin cysteines promotes synaptic multimerization and enhances inhibitory receptor clustering through disulfide bridges.

This study investigates a specific gephyrin microdeletion (Δ199-233) in a mouse model, showing disrupted synaptic function and neurological deficits linked to reduced inhibitory signal transmission.

This study shows that deleting Ox1R in dopaminergic neurons increases novelty-induced locomotion and exploration without affecting other behaviors.