Author

Andrew E. O. Hughes

Washington University in St. LouisORCID 0000-0001-7788-3655Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Joseph C. CorboiD· 3 shared Connie A. Myers· 2 shared Carlos Perez-CervantesiD· 1 shared Constance L. CepkoiD· 1 shared Daniel Murphy· 1 shared Duo XuiD· 1 shared Ivan P. G. MoskowitziD· 1 shared Jeong Sook Kim‐HaniD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMolecular Biology

Joseph C. CorboORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 28, 2021

A candidate causal variant underlying both enhanced cognitive performance and increased risk of bipolar disorder

Susan Q. Shen, Jeong Sook Kim‐Han, Lin Cheng…·Joseph C. Corbo

The paper identifies a candidate causal variant, rs77910749, that links enhanced cognitive performance with increased bipolar disorder risk through its effect on POU3F2 expression and amygdala function.

11 citations

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyDevelopmentPeer-reviewedJan 8, 2020

Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types

Rangarajan D. Nadadur, Carlos Perez-Cervantes, Nicolas Lonfat…·Ivan P. G. Moskowitz

The paper identifies cis-regulatory elements (CREs) for photoreceptor cell types using Nrl-dependent ncRNA profiling and ATAC-seq in mouse retina.

21 citations

mouseATAC-seq

𝕏 PostBluesky

Molecular BiologyeLifePeer-reviewedOct 21, 2019

Cis-regulatory basis of sister cell type divergence in the vertebrate retina

Daniel Murphy, Andrew E. O. Hughes, Karen A. Lawrence…·Joseph C. Corbo

The paper identifies cis-regulatory features distinguishing retinal photoreceptors and bipolar cells, showing motif partitioning drove transcriptome divergence.

40 citations

mouseChIP-seq

𝕏 PostBluesky