Xufen Yu

This paper identifies G9a's role in SARS-CoV-2-induced pathogenesis by regulating translation of viral and host proteins, showing that G9a inhibitors can reverse disease-related proteomic changes.

This study identifies G9a's noncanonical role in promoting translation of genes involved in hyperinflammation and lymphopenia in COVID-19, revealing therapeutic targets that counteract viral effects.

This paper develops cell-based assays to monitor PROTAC degradation kinetics and ternary complex formation, revealing that ternary complex stability is critical for PROTAC efficiency.