Author

Anja Dölle

Goethe University FrankfurtORCID 0000-0002-1816-8982Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas KrämeriD· 1 shared Janik WeckesseriD· 1 shared Jian Jun JiniD· 1 shared Krishna SaxenaiD· 1 shared Martin P. SchwalmiD· 1 shared Stefan KnappiD· 1 shared Xufen YuiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Andreas KrämerORCID

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1 paper

Recent·Most cited

Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization

Martin P. Schwalm, Andreas Krämer, Anja Dölle, Janik Weckesser, Xufen Yu, Jian Jun Jin, Krishna Saxena, Stefan Knapp

This paper develops cell-based assays to monitor PROTAC degradation kinetics and ternary complex formation, revealing that ternary complex stability is critical for PROTAC efficiency.

Cell chemical biology · Jun 24, 2023Peer-reviewedMolecular Biology