Thiago C. Moulin

This study shows that a single dose of DMT reverses depressive-like behaviors and cognitive deficits in a mouse model of depression by restoring neurogenesis.

This study shows that octopamine rapidly potentiates presynaptic neurotransmitter release in Drosophila by clustering Unc13 via diacylglycerol signaling, affecting synaptic function and behavior.

This review examines how psychedelic compounds affect neurogenesis and brain plasticity, finding varied effects across different classes of psychedelics.

This paper uses computational models to show that homeostatic plasticity can destabilize memories during reconsolidation, linking it to synaptic downscaling and behavioral effects of protein synthesis inhibition.

Phobos is a free, self-calibrating software for measuring freezing behavior that matches manual scoring reliability and reduces user variability.

This study shows that chronic optogenetic stimulation of hippocampal neurons reduces spine density, mEPSC amplitude, and impairs LTP while facilitating LTD.

This study reviews effect sizes and statistical power in rodent fear conditioning research, finding low power and inconsistent reporting of these metrics.

This paper reviews peripheral biomarkers in major psychiatric disorders, finding that five molecules show similar variation across disorders, suggesting transdiagnostic systemic consequences rather than specific diagnostic markers.