Alexander M. Walter

The paper shows how neural adaptation in fly olfactory neurons is compensated through circuit-level mechanisms to maintain background-invariant population codes.

The paper shows that mobile CaV2.1 channels enhance neurotransmitter release reliability at higher frequencies and are inhibited by GABABR activation.

This study shows that Bruchpilot remodeling couples synaptic structure to Kv1/Shaker channel control of excitability, restoring function in sleepless mutants.

This study shows that octopamine rapidly potentiates presynaptic neurotransmitter release in Drosophila by clustering Unc13 via diacylglycerol signaling, affecting synaptic function and behavior.

This study shows that a constitutively active form of Unc13A reduces sleep rebound after deprivation, suggesting a role for SNARE complex dynamics in sleep homeostasis.

This study identifies Blobby as a novel regulator of presynaptic active zone nanopatterning and shows its role in maintaining Ca2+ channel packing density and synaptic function.

This study identifies Doc2 as the major Ca2+ sensor for asynchronous release and shows that syt7 supports vesicle docking, with combined effects on synaptic function.

The paper shows that spontaneous neurotransmission at synapses predicts their responsiveness to action potentials in Drosophila NMJs.

This study identifies how Unc13A regulatory domains control synaptic plasticity by modulating release site participation in Drosophila synapses.

The paper models how synaptotagmins' dual Ca2+/PI(4,5)P2 binding stabilizes exocytosis by lowering the energy barrier for vesicle fusion.

The paper reveals a nanoscale tripartite complex at glutamatergic synapses formed by Ca2+-channels, vesicles, and AMPA receptors, showing their functional coordination in neurotransmission.

The paper identifies non-neuronal Synaptobrevin (Syb) as essential for glial function in Drosophila motoneurons, showing that disrupting Syb leads to nerve disintegration and paralysis.

The paper identifies a molecular mechanism for presynaptic plasticity involving rapid remodeling of active zone modules, which sustains neurotransmitter release potentiation over time.