Author

Zachary W. Kockler

National Institute of Environmental Health SciencesORCID 0000-0001-7828-3520Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:yeast· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Dmitry A. GordeniniD· 2 shared Leszek J. KlimczakiD· 2 shared Matthew S. DenneniD· 2 shared Steven A. RobertsiD· 2 shared Adam BurkholderiD· 1 shared Hamed BostaniD· 1 shared Jian‐Liang LiiD· 1 shared Ludmila M. PerelyginaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenetics

Dmitry A. GordeninORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

APOBEC3A is the predominant global editor of cytosines in human mRNAs and in single-strand RNA viruses

Zachary W. Kockler, Hamed Bostan, Leszek J. Klimczak, Yun-Chung Hsiao, Matthew S. Dennen, Molly E. Cook, Tony M. Mertz, Ludmila M. Perelygina, Marat D. Kazanov, Jian‐Liang Li, Steven A. Roberts, Dmitry A. Gordenin

The paper identifies APOBEC3A as the main RNA editor in human cells and viruses, showing its preference for specific motifs in mRNA and viral RNA.

G3 Genes Genomes Genetics · Mar 28, 2026Peer-reviewedGenetics

Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast

Matthew S. Dennen, Zachary W. Kockler, Steven A. Roberts, Adam Burkholder, Leszek J. Klimczak, Dmitry A. Gordenin

The paper shows that a hypomorphic mutation in RPA subunit rfa1-t33 in yeast enhances APOBEC-induced mutagenesis and alters mutation spectra.

G3 Genes Genomes Genetics · Aug 16, 2024Peer-reviewedGenetics