Sarthak M. Singhal

This study investigates how VTA dopamine neuron activity influences decision-making under risk of punishment in rats, finding that their activity scales with punishment probability and intensity and causally affects subsequent choices.

This study shows that mu-opioid receptor activation inhibits somatodendritic firing but enhances excitatory glutamate transmission at the habenulo-peduncular synapse.

This study challenges the traditional view of VTA interneurons by showing that GABA and glutamate projection neurons in the VTA also form local synapses, suggesting they may fulfill roles previously attributed to interneurons.

This study shows that VTA glutamate neurons can drive reward through glutamate release and aversion through dopamine co-release using optogenetic manipulation.

The paper investigates the neural circuits and cell-specific contributions to risk-taking behavior in male and female rats during decision-making tasks involving punishment.

This study uses optogenetics to show that basolateral amygdala activity at different decision-making phases influences risky choice in rats.