Lucie Oriol

The paper investigates how GABA-glutamate corelease in ventral tegmental area neurons affects neurotransmission in the lateral habenula, showing state-dependent excitatory or inhibitory effects and implications for motivation.

This study challenges the traditional view of VTA interneurons by showing that GABA and glutamate projection neurons in the VTA also form local synapses, suggesting they may fulfill roles previously attributed to interneurons.

The paper quantifies and maps neurotransmitter-defined cell types in VTA and SNc using fluorescent in situ hybridization, revealing diverse distributions and proportions.

This study identifies how VP GABA and glutamate neurons modulate VTA cell types to drive approach and avoidance behaviors through distinct mechanisms.