Brian C. Miller

This study identifies folate receptor beta (FRβ) as a metabolic checkpoint on tumor-associated macrophages (TAMs) that promotes immunosuppression and tumor growth.

This study compares immune phenotypes and activation states in bone marrow chimeras after irradiation with cesium-137 or X-ray sources, finding no significant differences.

This study identifies Dusp5 and Zfp219 as key regulators of age-related T cell dysfunction using CRISPR screens and shows their potential as therapeutic targets.

This study shows CD40 agonist therapy reduces tumor growth in antigen presentation-deficient tumors by reprogramming monocytes and requiring IFN-gamma and CD8+ T cells for efficacy.

The paper uses single-cell transcriptomics to study stress hormone effects on immune cells and identifies cell-type-specific changes linked to stress-related diseases.