Author

Matthew P. Zimmerman

University of North Carolina at Chapel HillORCID 0000-0002-2979-9624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Brian C. MilleriD· 3 shared Emily K. Cox· 3 shared Haiyang WangiD· 3 shared Wan Lin ChongiD· 3 shared Alexander Gevelinger Bastian· 2 shared Amy G. ReynoldsiD· 2 shared Katherine J. Vietor· 2 shared Vasyl ZhabotynskyiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Brian C. MillerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Folate metabolism in tumor-associated macrophages drives immunosuppressive function to promote tumor growth

Matthew P. Zimmerman, Vasyl Zhabotynsky, Haiyang Wang, Emily K. Cox, Wan Lin Chong, Alexander Gevelinger Bastian, Andrew S. Kennedy, Brian P Fay, Amy G. Reynolds, Anna Ebacher, Jeremy A. Meier, Katherine J. Vietor, Khalilah E. Taylor, Pristine C. Onuoha, Siddharth Maruvada, , Brian C. Miller

This study identifies folate receptor beta (FRβ) as a metabolic checkpoint on tumor-associated macrophages (TAMs) that promotes immunosuppression and tumor growth.

bioRxiv · Oct 2, 2026 · PreprintImmunology

Cesium-137 and X-Ray Irradiation Yield Comparable Immune Phenotypes and Activation States in Bone Marrow Chimeric Studies

Alexander Gevelinger Bastian, Eric W. Livingston, Matthew P. Zimmerman, Amy G. Reynolds, Wan Lin Chong, Emily K. Cox, Haiyang Wang, Hong Yuan, Brian C. Miller

This study compares immune phenotypes and activation states in bone marrow chimeras after irradiation with cesium-137 or X-ray sources, finding no significant differences.

bioRxiv · Aug 28, 2026 · PreprintImmunology

Harnessing Inflammatory Monocytes to Overcome Resistance to Anti-PD-1 Immunotherapy

Matthew P. Zimmerman, Amy Y. Huang, Emily K. Cox, Rose Al Abosy, Wan Lin Chong, Alex Bastian, Katherine J. Vietor, Yacine A. Choutri, Jenna L. Collier, Vasyl Zhabotynsky, Haiyang Wang, Megan E. Fung, Sarah A. Weiss, Emily J. Robitschek, Jia‐Ren Lin, , Brian C. Miller

This study shows CD40 agonist therapy reduces tumor growth in antigen presentation-deficient tumors by reprogramming monocytes and requiring IFN-gamma and CD8+ T cells for efficacy.

bioRxiv · Feb 8, 2026 · PreprintImmunology