Author
Oregon Health & Science UniversityORCID 0009-0008-1915-3660Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Kevin Hawthorne, Jennifer R. Eng, Motoyuki Tsuda…·Rosalie C. Sears
The paper identifies subtype-intermediate progenitor cells in pancreatic cancer with distinct epigenetic profiles linked to clinical outcomes and lineage reprogramming.
Motoyuki Tsuda, Dove J. Keith, Colin J. Daniel…·Rosalie C. Sears
The paper identifies resistance mechanisms to KRAS-MEK pathway targeting in PDAC by analyzing clinical trial data and multi-omics profiles, showing that KRAS/MYC co-gain correlates with resistance and that co-targeting these genes is synergistic.
Katherine R. Pelz, Philip Jimenez, Colin J. Daniel…·Teresa A. Zimmers
This paper introduces a dual-contrast microCT protocol to track tumor growth, metastasis, and cachexia in murine PDAC models over time.
Yifei Guo, Jennifer M. Finan, Alexandra Q. Bartlett…·Robert L Eil
This study shows that HuR promotes immune evasion in PDAC by inhibiting T cell infiltration and function, suggesting HuR as a therapeutic target with immunotherapy.
Vidhi M. Shah, Alexandra Q. Bartlett, Canping Chen…·Rosalie C. Sears
This study shows PIN1 promotes cellular plasticity and immune changes in chronic pancreatitis, with genetic or pharmacological inhibition reducing disease severity.