Author

I. R. Horak

Masaryk UniversityORCID 0000-0001-7880-9713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Adela KubistovaiD· 1 shared Jan SkodaiD· 1 shared Jaroslav ŠtěrbaiD· 1 shared Karolina BorankovaiD· 1 shared Marie ŠulováiD· 1 shared Martin MarekiD· 1 shared Tomáš BártaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adela KubistovaORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 1, 2026

Cumate-inducible models of MYC-driven neuroblastoma identify mitoribosomal synthetic lethality as a precision oncology vulnerability in MYC(N)-amplified tumors

Adela Kubistova, I. R. Horak, Tomáš Bárta…·Jan Skoda

This paper develops a cumate-inducible model to study MYC-driven neuroblastoma and identifies mitoribosomal synthetic lethality as a therapeutic target in MYC(N)-amplified tumors.

DOI 10.64898/2026.05.25.725359

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 27, 2024

Analysis of publicly available transcriptomic data to identify key genes and pathways associated with osteosarcoma metastasis

I. R. Horak

This study analyzes 8 publicly available transcriptomic datasets to identify common deregulated genes and pathways associated with osteosarcoma onset and metastasis.

DOI 10.1101/2024.11.27.623785

humanbulk RNA-seq

𝕏 PostBluesky