Author

Zlata Gvozdenov

Harvard UniversityORCID 0000-0001-7898-1660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Kevin StruhliD· 2 shared Zeno Barcutean· 2 shared Anusmita Biswas· 1 shared Audrey Yi Tyan PengiD· 1 shared Brian FreemaniD· 1 shared Daniel R. GestautiD· 1 shared Judith FrydmaniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Kevin StruhlORCID

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3 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedSep 1, 2026

TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis

Zlata Gvozdenov, Anusmita Biswas, Audrey Yi Tyan Peng…·Brian Freeman

This study shows TRiC/CCT regulates RNA polymerase II activity in the nucleus, affecting RNA homeostasis by modulating nascent RNA production.

3 citations

experimental assay

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GenomicsCurrent ProtocolsPeer-reviewedApr 1, 2023

Genome-Wide Mapping of 5' Isoforms with 5'-Seq

Zlata Gvozdenov

The paper describes a protocol for generating and analyzing 5' isoform sequencing data to study transcriptome complexity.

DOI 10.1002/cpz1.750

whole-genome sequencingexperimental assay

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Molecular BiologybioRxivPreprintOct 26, 2022

High level and molecular nature of transcriptional noise in yeast cells

Zlata Gvozdenov, Zeno Barcutean, Kevin Struhl

This study measures transcriptional noise in yeast by analyzing random-sequence DNA and finds higher cell-to-cell variability in RNAs from random-sequence DNA compared to yeast genomic DNA.

3 citations

yeastDNA methylation

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