Author

Brian Freeman

University of Illinois Urbana-ChampaignORCID 0000-0003-1993-8974Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 1

Frequent Co-Authors

Audrey Yi Tyan PengiD· 2 shared Anusmita Biswas· 1 shared Daniel R. GestautiD· 1 shared Jianhui LiiD· 1 shared Judith FrydmaniD· 1 shared Kevin StruhliD· 1 shared Zeno Barcutean· 1 shared Zlata GvozdenoviD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersMolecular Biology

Audrey Yi Tyan PengORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedSep 1, 2026

TRiC/CCT Chaperonin Governs RNA Polymerase II Activity in the Nucleus to Support RNA Homeostasis

Zlata Gvozdenov, Anusmita Biswas, Audrey Yi Tyan Peng…·Brian Freeman

This study shows TRiC/CCT regulates RNA polymerase II activity in the nucleus, affecting RNA homeostasis by modulating nascent RNA production.

3 citations

experimental assay

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GenomicsbioRxivPreprintSep 26, 2024

Nuclear Type I Myosins are Essential for Life and Genome Organization

Audrey Yi Tyan Peng, Jianhui Li, Brian Freeman

This study shows that nuclear type I myosins are essential for yeast cell viability and genome organization, with their depletion causing 3D genome disorganization and nuclear structural defects.

2 citations

yeastexperimental assay

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