Alexandre Bokhobza

This paper uses nanopore long-read sequencing to detect CFTR variants in Moroccan individuals, identifying new pathogenic variants and demonstrating the utility of the method for genetic screening in African populations.

The paper characterizes MINFLUX imaging performance over extended durations using DNA origami and corrects residual drift, achieving sub-2 nm precision without loss of site precision.

The paper investigates optimizing labeling efficiency in MINFLUX 3D DNA-PAINT microscopy by improving marker detection probability through repeat DNA-PAINT and adjusting acquisition parameters.

The paper introduces Shielded DNA-PAINT, a method to reduce non-specific DNA-PAINT probe binding in cells, achieving a 5-fold reduction in non-specific events in the nucleus.