Alexandria B. Marciante

This study investigates how daily acute intermittent hypoxia (dAIH), age, and sex affect molecules regulating phrenic motor plasticity in rats, finding age- and sex-dependent changes in gene expression related to signaling pathways involved in respiratory motor facilitation.

This study shows microglia regulate respiratory neuroplasticity through fractalkine/adenosine signaling, with distinct roles in moderate and severe hypoxia-induced plasticity.

This study identifies APOE4 genotype, sex, and age as factors influencing the respiratory plasticity response to acute intermittent hypercapnic-hypoxia in healthy adults.