Gordon S. Mitchell

This study shows systemic hypoxia promotes lung adenocarcinoma progression by mobilizing glycogen via GAA, supporting tumor growth through metabolic remodeling.

This paper constructs a spatial metabolomic atlas of exercise in mice, identifies Complex I as a key target for reducing tau pathology, and shows that enhancing its activity mimics exercise's protective effects.

This study investigates how daily acute intermittent hypoxia (dAIH), age, and sex affect molecules regulating phrenic motor plasticity in rats, finding age- and sex-dependent changes in gene expression related to signaling pathways involved in respiratory motor facilitation.

This study shows microglia regulate respiratory neuroplasticity through fractalkine/adenosine signaling, with distinct roles in moderate and severe hypoxia-induced plasticity.

This study identifies APOE4 genotype, sex, and age as factors influencing the respiratory plasticity response to acute intermittent hypercapnic-hypoxia in healthy adults.