Author

Junko Itô

Brain Research Institute, Niigata UniversityORCID 0000-0001-7958-1052Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Akihiro SugaiiD· 1 shared Akio YokosekiiD· 1 shared Akiyoshi KakitaiD· 1 shared Mari TadaiD· 1 shared Norikazu HaraiD· 1 shared Osamu OnoderaiD· 1 shared Shintaro TsuboguchiiD· 1 shared Takeshi IkeuchiiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Akihiro SugaiORCID

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1 paper

Recent·Most cited

Molecular BiologyCommunications BiologyPeer-reviewedSep 21, 2021

Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex

Yuka Mitsuhashi Koike, Akihiro Sugai, Norikazu Hara…·Osamu Onodera

The paper shows that age-related DNA demethylation in the TARDBP 3'UTR reduces alternative splicing and increases TARDBP mRNA expression in the human motor cortex, linking this to earlier ALS onset.

28 citations

humanDNA methylation

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