Author

Chengmin Li

University of California, San FranciscoORCID 0000-0001-7969-9990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Hao Wu· 2 shared Yifan ChengiD· 2 shared Elise N. MuñoziD· 1 shared Geeta J. NarlikariD· 1 shared Upneet KauriD· 1 shared Woo-Young ChoiiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

Hao Wu

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintAug 18, 2026

ATP-dependent reorientation on a nucleosome primes INO80 for DNA translocation

Hao Wu, Upneet Kaur, Chengmin Li…·Yifan Cheng

This study reveals that INO80 reorients on a nucleosome upon ATP hydrolysis, enabling DNA translocation through a unique mechanism distinct from other chromatin remodelers.

DOI 10.64898/2026.08.11.744281

cryo-EMexperimental assay

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BiophysicsbioRxivPreprintJul 4, 2026

CryoROLE: describing large inter-domain rotation in single particle cryo-EM

Chengmin Li, Woo-Young Choi, Hao Wu, Yifan Cheng

CryoROLE extracts continuous conformational dynamics from cryo-EM data by analyzing relative domain orientations, revealing hidden protein motions relevant to function.

1 citation

cryo-EMdeep learning

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