NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain.
Luke A. Pattison, Rebecca H. Rickman, Helen Hilton…·Ewan St. John Smith
This study shows that activating GPR65 on fibroblast-like synoviocytes leads to inflammatory mediator release, contributing to joint pain in mice and humans.