Claire Wilson

This study shows that 7SK-snRNP components HEXIM1 and LARP7 promote replication fork reversal and homologous recombination under transcription and replication stress, independent of BRCA1.

The paper identifies and characterizes CpG islands in 3'UTRs, showing their conservation, methylation patterns, and association with cancer-related gene expression changes.

This study shows that PI3K-AKT activation is required for RAS-induced replication stress and hypertranscription in cancer cells.

This study shows that RNase H2 upregulation mitigates replication stress caused by oncogenes and chemotherapy, reducing replication fork stalling and RNA:DNA hybrids.

The paper shows that CCDC26 RNA regulates DNMT1 nuclear localisation, affecting DNA methylation and cell viability.