Thomas M. D. Combriat

The paper develops a kinetic model to distinguish between matrix-associated and solution-driven calcium phosphate mineralization in osteogenic cultures and shows that total mineral amount does not indicate matrix contribution.

This paper introduces a cellular automaton model to study osteogenic differentiation and shows endpoint assays have limited ability to distinguish underlying mechanisms.

This paper uses quantitative phase imaging to study 3D dynamics of epithelial monolayers, revealing mass conservation and non-prismatic cell geometry challenges to 2.5D assumptions.

This study measures height, volume, and mass dynamics of MDCK monolayers using two QPI techniques and develops new methods for cell segmentation and height statistics without image segmentation.

The paper describes a modular co-aggregation strategy to recreate embryonic-extraembryonic interactions in vitro, leading to more complex gastruloid morphotypes with improved lineage diversity and patterning.