Author

Marcelo Luciano Merli

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0001-7994-4140Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

Julia A. CriccoiD· 3 shared Marı́a G. MediavillaiD· 3 shared Carlos RobelloiD· 1 shared Cecilia Beatriz Di CapuaiD· 1 shared Elvio Rodríguez ArayaiD· 1 shared Esteban Carlos SerraiD· 1 shared Evelyn TevereiD· 1 shared Exequiel O. J. PortaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiochemistry

Julia A. CriccoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiochemistryBioorganic & Medicinal ChemistryPeer-reviewedAug 29, 2026

Functional Mapping of the Trypanosoma cruzi Serinome by Fluorophosphonate Activity-Based Protein Profiling

Jaime A. Isern, Marı́a G. Mediavilla, Exequiel O. J. Porta…·Patrick G. Steel

This study maps the serinome of Trypanosoma cruzi using fluorophosphonate activity-based protein profiling, identifying 37 SH-like proteins and their functional roles.

DOI 10.1016/j.bmc.2026.118793

proteomicsexperimental assay

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BiochemistrybioRxivPreprintJul 14, 2025

Transcriptomic response to different heme sources in Trypanosoma cruzi

Evelyn Tevere, Marı́a G. Mediavilla, Cecilia Beatriz Di Capua…·Julia A. Cricco

This study examines how different heme sources affect gene expression in Trypanosoma cruzi, identifying novel heme-responsive genes and proteins.

DOI 10.1101/2025.07.14.664770

bulk RNA-seqexperimental assay

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MicrobiologyFEBS JournalPeer-reviewedDec 5, 2024

Copper trafficking in Trypanosoma cruzi: the transcriptional response of candidates to balance toxicity and recruitment

Marcelo Luciano Merli, María G. Mediavilla, Xinyu Zhu…·Julia A. Cricco

This study investigates copper metabolism in Trypanosoma cruzi, identifying key genes and proposing a model for copper transport and distribution during different life stages.

4 citations

bulk RNA-seqexperimental assay

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Molecular BiologyACS Infectious DiseasesPeer-reviewedMay 11, 2023

Deciphering divergent trypanosomatid nuclear complexes by analyzing interactomic datasets with AlphaFold2 and genetic approaches

Elvio Rodríguez Araya, Marcelo Luciano Merli, Pamela Cribb…·Esteban Carlos Serra

The paper uses AlphaFold2 and genetic approaches to identify protein complexes in trypanosomatids, revealing structurally conserved and novel complexes involving MRG domain-containing proteins.

7 citations

protein structuredeep learning

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