Danica S. Cui

This paper introduces a method to improve NMR resonance assignment by modulating metabolic flux during protein expression, using 15N-enriched media with natural abundance media to create unique peak patterns.

The paper investigates how amino acid limitation affects translation by analyzing ribosome stalling and the role of RQC pathways and RNF14 in response to arginine depletion.

The paper develops a method to globally monitor protein degradation in yeast and finds that bulk and selective autophagy cooperatively drive proteome remodeling in response to nutrient changes.

This study quantifies proteome dynamics during mTOR inhibition, revealing distinct kinetics between proteasomal and lysosomal degradation and coordinated synthesis-degradation of translation factors.