Hannes Mutschler

This study demonstrates the use of the bacterial retron system Eco2 to express a DNA aptamer intracellularly in E. coli, showing comparable activity to chemically synthesized controls.

This study shows a group II intron can perform DNA hydrolysis and self-integration without protein cofactors, expanding its catalytic capabilities and suggesting a protein-free origin.

This study shows that ribozyme activity in coacervate droplets enhances polymer length and alters droplet behavior, linking genotype to phenotype in protocells.