Daniel Summerer

HM-DyadCap captures and maps hmC/mC CpG dyads in mammalian DNA, revealing their enrichment in gene bodies and depletion at transcription start sites.

The paper identifies symmetry-specific readers and anti-readers of 5-formylcytosine (fC) in mammalian DNA using proteomics, revealing how proteins recognize fC-containing CpG dyads with distinct symmetry preferences.

This study demonstrates the use of the bacterial retron system Eco2 to express a DNA aptamer intracellularly in E. coli, showing comparable activity to chemically synthesized controls.

The paper identifies tissue-specific readers and antireaders of symmetric and asymmetric hmC modifications in DNA using proteomics and promoter probe assays in human and mouse cells.

The paper investigates how a designer DNA reader selectively recognizes oxidized CpG duplex marks through conformational plasticity, revealing insights into DNA-protein interactions.