NeurosciencebioRxivPreprint
Ectopic engraftment of nociceptive neurons derived from hPSCs for pain relief and joint homeostasis
Zhuolun Wang, Weixin Zhang, Ju Wang…·Xinzhong Dong
This paper demonstrates that transplanting CD200-high hPSC-derived nociceptors reduces pain and promotes joint repair in osteoarthritis by acting as decoys for inflammatory ligands and secreting reparative factors.
DOI 10.64898/2025.12.16.694733