Cancer BiologybioRxivPreprint
Multiple mechanisms regulate the nanoscale organization of PD-L1 at the cell surface
Guus A. Franken, Abbey B. Arp, Dora Čerina…·Annemiek B. van Spriel
This study investigates how PD-L1 is organized into nanoscale clusters on tumor cell surfaces and identifies actin cytoskeleton, galectin-3, and cholesterol as key regulators of its spatial arrangement and function.