Author
Yasuko Iwakiri
Yale UniversityORCID 0000-0001-8032-5654Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 37 mutual co-author links5 papers
Recent·Most cited
- PathologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewed
Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages
Ruixue Ma, Li Gong, Chao Dong…·Yasuko Iwakiri
This study shows that increased VCAM-1 in hepatic artery endothelial cells and portal fibroblasts recruits Spp1+ macrophages, driving fibrosis in portal hypertension.
4 citationstop 2% - PathologybioRxivPreprint
Liver Lymphatic Dysfunction as a Driver of Fibrosis and Cirrhosis Progression
Jain Jeong, Shao‐Jung Hsu, Daiki Horikami…·Yasuko Iwakiri
This study shows that impaired liver lymphatic function drives fibrosis and cirrhosis progression and identifies VEGF-C as a potential therapeutic target.
3 citations - Molecular BiologyJournal of HepatologyPeer-reviewed
Alcohol-induced Hsp90 acetylation is a novel driver of liver sinusoidal endothelial dysfunction and alcoholic liver disease
Yilin Yang, Panjamaporn Sangwung, Reiichiro Kondo…·Yasuko Iwakiri
This study shows that alcohol-induced Hsp90 acetylation in liver sinusoidal endothelial cells (LSECs) reduces eNOS interaction and NO production, contributing to alcoholic liver disease, and suggests HDAC6 overexpression as a therapeutic approach.
- NeuroscienceGastroenterologyPeer-reviewed
Enhanced meningeal lymphatic drainage ameliorates neuroinflammation and hepatic encephalopathy in cirrhotic rats
Shao‐Jung Hsu, Chihao Zhang, Jain Jeong…·Yasuko Iwakiri
This study shows that enhancing meningeal lymphatic drainage reduces neuroinflammation and improves motor function in cirrhotic rats with hepatic encephalopathy.
125 citationstop 2%