Author

Carine De Marcos Lousa

University of DundeeORCID 0000-0002-5041-6261Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:protein structure· 2 Organism:plant (other)· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adrian GoldmaniD· 1 shared Ana J Loureiro LevadaiD· 1 shared Andrew C.H. Liu· 1 shared Andrew QuigleyiD· 1 shared Glenn Robert MassoniD· 1 shared Isabel UsóniD· 1 shared Jing AniD· 1 shared Joanne E. NettleshipiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPlant Biology

Adrian GoldmanORCID

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2 papers

Recent·Most cited

Structural Basis for Activation of HRI by the DELE1 C-terminal domain

Olawale G. Raimi, Rupam Bhattacharjee, Min Cao, Shannon Richardson, Andrew C.H. Liu, Vanesa Vinciauskaite, Carine De Marcos Lousa, Miratul M. K. Muqit, Glenn Robert Masson

This paper shows that DELE1CTD binds to HRI's N-terminal region, displacing haem and activating HRI through competition for the haem-binding site.

bioRxiv · Sep 17, 2026 · PreprintBiochemistry

The two crystal structures of unloaded and cargo-loaded Vacuolar Sorting Receptor 1 lumenal domain (VSR1-Nt) reveal two cargo binding sites and a mechanism of transport.

Rafael J. Borges, Mahmoud K. Eldahshoury, Rebecca J. Parr, Marilyn Paul, Paul K. Fyfe, Joanne E. Nettleship, Jing An, Nita R. Shah, Ana J Loureiro Levada, Marcos R.M. Fontes, Raymond J. Owens, Jürgen Denecke, Andrew Quigley, Adrian Goldman, Vincent L. G. Postis, , Carine De Marcos Lousa

The paper determines the crystal structures of unloaded and cargo-loaded VSR1-Nt, revealing two cargo binding sites and a calcium-dependent mechanism for cargo binding and release.

bioRxiv · Dec 7, 2024 · PreprintPlant Biology