BiochemistryCardiovascular ResearchPeer-reviewed
Drp1-mediated mitochondrial fission protects macrophages from mtDNA/ZBP1-mediated sterile inflammation and inhibits post-infarct cardiac remodeling
Yuki Kondo, Jun‐ichiro Koga, Nasanbadrakh Orkhonselenge…·Masaharu Kataoka
This study shows that Drp1 in macrophages prevents mtDNA release and inflammation, reducing cardiac remodeling after heart attack.
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