Author

Saikat Chowdhury

Centre for Cellular and Molecular BiologyORCID 0000-0001-8043-5028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Brandon A. IrizarryiD· 1 shared Elliot J. CrooksiD· 1 shared Gabriel C. LanderiD· 1 shared Ian J. MacRaeiD· 1 shared Siobhan M. Hughes· 1 shared Steven O. SmithiD· 1 shared Todd A. AnzeloniD· 1 shared William E. Van NostrandiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Brandon A. IrizarryORCID

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2 papers

Recent·Most cited

An electrostatic cluster guides Abeta fibril formation in cerebral amyloid angiopathy

Elliot J. Crooks, Ziao Fu, Brandon A. Irizarry, Xiaoyue Aelita Zhu, William E. Van Nostrand, Saikat Chowdhury, Steven O. Smith

The paper identifies an electrostatic cluster in A{beta}40 fibrils from CAA patients that influences fibril formation and differs from AD fibrils.

bioRxiv · Dec 22, 2022 · PreprintNeuroscience

Structural basis for piRNA-targeting

Todd A. Anzelon, Saikat Chowdhury, Siobhan M. Hughes, Yao Xiao, Gabriel C. Lander, Ian J. MacRae

This paper presents cryo-EM structures of Piwi-piRNA complexes and analyzes their target recognition mechanism, revealing how Piwi ensures targeting fidelity and adapts to genomic threats.

Nature · Sep 1, 2021Peer-reviewedMolecular Biology