Ziao Fu

This study shows lipid bilayers enable cooperative cAMP binding to HCN channels but do not affect intrinsic binding affinity, revealing a role for membranes in enhancing inter-subunit interactions.

This study identifies how CatSper channels integrate temperature and pH signals through structural and evolutionary analyses in sperm.

The paper presents the cryo-EM structure of a nematode LGR dimer, providing insights into the evolution and function of glycoprotein hormone receptors.

The paper reports the cryo-EM structure of the human Stomatin complex, revealing its role in forming membrane microdomains and providing insights into its mechanical properties and disease relevance.

This study determines the structure of the Flotillin complex in a native membrane environment using cryo-electron microscopy, revealing its role in membrane curvature and isolation of biochemical processes.

The paper identifies an electrostatic cluster in A{beta}40 fibrils from CAA patients that influences fibril formation and differs from AD fibrils.

This study uses time-resolved cryo-EM to visualize the conformational changes during bacterial 70S initiation complex formation and maturation into an elongation-competent complex.