Songying Zhang

The paper uses cryo-EM to reveal the high-resolution structure of mouse oocyte cytoplasmic lattices, identifying their components and hierarchical assembly mechanism.

This study identifies pro-inflammatory macrophages as key regulators of the PE-specific immune microenvironment, linking them to Th17 and CD8+ T cell activation and gMDSC suppression in placental tissues.

This study develops ac4C LACE-seq to profile mRNA N4-acetylation in mouse oocytes and shows NAT10 is essential for ac4C modification, which enhances translation efficiency during meiotic maturation.