BiochemistrybioRxivPreprint
Interferon redundancy counteracts proteolytic inactivation by SARS-CoV-2 3CL main protease
Peter M. Grin, Hugo César Ramos de Jesus, Isabel Pablos…·Christopher M. Overall
This study shows that SARS-CoV-2 3CLpro protease inactivates specific interferons by cleaving glycosylated variants, but interferon redundancy maintains antiviral activity.
DOI 10.64898/2026.09.07.749787