Author

Peter M. Grin

University of BernORCID 0000-0001-9504-9664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:non-human primate· 1

Frequent Co-Authors

Charaf BenarafaiD· 2 shared Charlene Constant· 1 shared Christopher M. OveralliD· 1 shared Étori Aguiar MoreiraiD· 1 shared Georgina S. ButleriD· 1 shared Gert ZimmeriD· 1 shared Hugo César Ramos de JesusiD· 1 shared Isabel PablosiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Charaf BenarafaORCID

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2 papers

Recent·Most cited

Interferon redundancy counteracts proteolytic inactivation by SARS-CoV-2 3CL main protease

Peter M. Grin, Hugo César Ramos de Jesus, Isabel Pablos, Reinhild Kappelhoff, Georgina S. Butler, Charaf Benarafa, Christopher M. Overall

This study shows that SARS-CoV-2 3CLpro protease inactivates specific interferons by cleaving glycosylated variants, but interferon redundancy maintains antiviral activity.

bioRxiv · Sep 8, 2026 · PreprintBiochemistry

A bovine-derived influenza A virus (H5N1) shows efficient replication in well-differentiated human nasal epithelial cells at the temperature of the upper airways

Étori Aguiar Moreira, Samuel Constant, Charlene Constant, Lisa Butticaz, Michele Wyler, Teodora David, Peter M. Grin, Charaf Benarafa, Volker Thiel, Marco P. Alves, Gert Zimmer

This study shows that a bovine-derived H5N1 virus replicates efficiently in human nasal epithelial cells at both 37°C and 33°C, with specific mutations enhancing replication at lower temperatures.

bioRxiv · May 22, 2026 · PreprintMicrobiology