José C. Mateus

This paper transfers reinforcement learning policies from in silico neuronal networks to in vitro cultures to control neuronal activity efficiently.

The paper tests asymmetric microchannel designs to promote unidirectional connectivity in cultured neuronal circuits and finds that the 'Rams' design achieves ~76% unidirectional connections and ~94% directional spiking activity.

This paper develops flexible microelectrode arrays (MEAs) for recording neuronal activity in 3D cultures, showing improved performance and scalability.

This paper develops a method to pattern neuronal circuits in vitro using nanoscale structures to guide synapse formation between isolated neuron groups.

The paper presents a method to create topologically controlled circuits of human iPSC-derived neurons for long-term electrophysiology recordings.

The paper shows that EAPs and antidromic conduction occur in neuronal cultures and can depolarize the soma, suggesting functional roles in neuronal activity.