Sean M. Weaver

The paper introduces hydroMEA, a 3D hydrogel-based microfluidic device that enables real-time electrophysiological measurements of myelinated nerve-on-chip systems using human iPSC-derived neurons and Schwann cells.

This paper develops an implantable biohybrid nerve model for synaptic deep brain stimulation, demonstrating in vitro and in vivo functionality for over 22 days.

This paper demonstrates in vitro neuronal networks capable of performing Boolean computations like NAND and OR using controlled topology and extracellular stimulation.

This paper introduces a scalable neural recording system using nanocapacitor arrays with code division multiplexing, enabling simultaneous recordings from 1,024 electrodes.

This study investigates how microchannel width and spatial constraints affect axon growth in brain-on-chip systems, finding that restrictions smaller than 350nm prevent axon penetration.

This paper develops a method to pattern neuronal circuits in vitro using nanoscale structures to guide synapse formation between isolated neuron groups.

The paper presents a method to create topologically controlled circuits of human iPSC-derived neurons for long-term electrophysiology recordings.