Author

Kangsan Roh

Harvard UniversityORCID 0000-0001-8067-7772Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Rajeev Kumar MalhotraiD· 2 shared Adam L. JohnsoniD· 1 shared Benjamin P. KleinstiveriD· 1 shared C.K. Fong· 1 shared Casey A. MaguireiD· 1 shared Catherine M. ShanahaniD· 1 shared Christian Lacks Lino CardenasiD· 1 shared Christiano R. R. AlvesiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Rajeev Kumar MalhotraORCID

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2 papers

Recent·Most cited

BioengineeringNature Biomedical EngineeringPeer-reviewedSep 11, 2025

In vivo Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor

Christiano R. R. Alves, Sabyasachi Das, Vijai Krishnan…·Patricia Leonor Musolino

This paper develops a customized CRISPR-Cas9 base editor to correct the ACTA2 R179H mutation in a mouse model of MSMDS, improving survival and rescuing vascular and neurological phenotypes.

13 citations

mousegenetic perturbation / CRISPR

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Cell BiologybioRxivPreprintJul 8, 2025

A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification

Sujin Lee, Yugene Y. Guo, Lova Prasadareddy Kajuluri…·Rajeev Kumar Malhotra

This study identifies FNDC1 as a key regulator of vascular calcification through the FNDC1-NAMPT-NAD axis, showing its role in both microvascular and macrovascular diseases and its potential as a therapeutic target.

DOI 10.1101/2025.07.08.663801

humanmouse

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