Author

Catherine M. Shanahan

King's College LondonORCID 0000-0002-8352-8171Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Clint L. MilleriD· 2 shared Elizabeth Moore· 2 shared Sadia AhmadiD· 2 shared Sujin LeeiD· 2 shared Adam L. JohnsoniD· 1 shared Andrew Durham· 1 shared Audrey KellyiD· 1 shared Chin‐Yee Ho· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Clint L. MillerORCID

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Author profile →

3 papers

Recent·Most cited

An ncBAF-ETS2 Chromatin-Remodelling Axis Drives Vascular Smooth Muscle Cell Osteogenic Reprogramming in Vascular Calcification

Mengying Wu, Jirapath Thammaphet, Audrey Kelly, Samara Banday, Sadia Ahmad, Chin‐Yee Ho, Sujin Lee, Elizabeth Moore, Rajeev Malhotra, Clint L. Miller, Konstantinos Theofilatos, Paul Lavender, Andrew Durham, Catherine M. Shanahan

bioRxiv · Aug 24, 2026 · PreprintCell Biology

A Novel FNDC1-NAMPT-NAD axis is Implicated in Small and Large-vessel Arterial Disease and Drives Vascular Calcification

Sujin Lee, Yugene Y. Guo, Lova Prasadareddy Kajuluri, Kangsan Roh, Kuldeep Singh, Wanlin Jiang, Elizabeth Moore, Helena Tattersfield, Katrina F. Ostrom, Claire Birchenough, Adam L. Johnson, Scott Krinsky, Houda Bouchouari, Mohammed Mohammedeh, Laurel Yong-Hwa Lee, , Rajeev Kumar Malhotra

This study identifies FNDC1 as a key regulator of vascular calcification through the FNDC1-NAMPT-NAD axis, showing its role in both microvascular and macrovascular diseases and its potential as a therapeutic target.

bioRxiv · Jul 8, 2025 · PreprintCell Biology

Sox9 accelerates vascular ageing by regulating extracellular matrix composition and stiffness.

Maria Faleeva, Sadia Ahmad, Steven Lynham, Gabriel C. Watson, Meredith Whitehead, Susan Cox, Catherine M. Shanahan

This study shows Sox9 regulates ECM stiffness and composition in vascular smooth muscle cells, promoting vascular ageing through a feedback loop between senescence and ECM changes.

bioRxiv · May 3, 2023 · PreprintMolecular Biology