Author

Aline Huguet-Lachon

InsermORCID 0000-0001-8072-2991Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:Drosophila· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Geneviève GourdoniD· 3 shared Nerea Moreno· 2 shared Ruben D. ArteroiD· 2 shared A LópeziD· 1 shared Adolfo López de MunainiD· 1 shared Alex Chun KooniD· 1 shared Ana Díaz-Maqueda· 1 shared Anchel González‐BarrigaiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersGenetics

Geneviève GourdonORCID

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3 papers

Recent·Most cited

GeneticsThe American Journal of Human GeneticsPeer-reviewedFeb 20, 2026

Enhanced muscle uptake of chemically optimized miR-23b antisense oligonucleotides as lead compounds for Myotonic Dystrophy type 1

Irene González-Martínez, Estefanía Cerro-Herreros, Marc Carrascosa-Sàez…·Ruben D. Artero

This study develops chemically optimized miR-23b antimiRs that enhance muscle uptake and restore MBNL1 function in DM1 models, showing improved efficacy and safety.

4 citationstop 2%

humanmouse

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NeurosciencebioRxivPreprintMay 26, 2024

Upregulation of FasII underlies synergistic neuropathological and behavioral defects in a Drosophila model of myotonic dystrophy

Alex Chun Koon, Ka Yee Winnie Yeung, Lok I Leong…·Ho Yin Edwin Chan

This study identifies FasII upregulation as a key factor in DM1 neuropathology using a Drosophila model, showing that manipulating FasII isoforms can rescue synaptic and behavioral defects.

DOI 10.1101/2024.05.26.595976

Drosophilaexperimental assay

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GenomicseLifePeer-reviewedDec 12, 2019

Straightjacket/α 2δ 3 deregulation is associated with cardiac conduction defects in Myotonic Dystrophy type 1

Emilie Auxerre-Plantié, Masayuki Nakamori, Yoan Renaud…·Krzysztof Jagla

The paper identifies straightjacket/α2δ3 deregulation as a contributor to cardiac conduction defects in DM1 by showing its overexpression in fly models and human patients.

14 citations

Drosophilamouse

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