Krzysztof Jagla

This study shows that the Drosophila RYR gene is essential for muscle development and function and demonstrates its utility in assessing human RYR1 mutations.

The paper identifies Amalgam and Neurotactin as molecular mediators of cell-cell communication between leg muscle and tendon precursors in Drosophila.

This study identifies miR-1 and its target Multiplexin as key regulators in DM1-associated dilated cardiomyopathy using Drosophila models.

This study shows that Ssdp regulates Wg expression and somatic muscle identity in Drosophila embryos, affecting muscle morphology and function through intrinsic and extrinsic mechanisms.

The paper identifies Gelsolin and dCryAB as downstream effectors of muscle identity genes that prevent muscle splitting and branching in Drosophila.

The paper shows that Drosophila adult muscle precursor cells guide motor axon pathfinding and proper muscle innervation through dynamic interactions with motor neurons.

This study identifies CAP and MSP-300 as proteins involved in cardioblast migration in Drosophila by linking focal adhesions to nuclei via the actin cytoskeleton.

The paper identifies straightjacket/α2δ3 deregulation as a contributor to cardiac conduction defects in DM1 by showing its overexpression in fly models and human patients.