Anna C. H. Hoge

The paper compares somatic mutations and aneuploidy in lung adenocarcinomas from never-smokers and smokers, finding that mutations, not copy number changes, distinguish the two groups.

This study identifies distinct structural variation patterns in prostate cancer across disease states, defining clinically actionable subgroups based on whole genome profiling.

The paper identifies a non-responder phenotype in the murine gut microbiome that exhibits resistance to cefoperazone, showing upregulated antimicrobial resistance genes and reduced central metabolism during antibiotic treatment.