Stephen Andrew Semick

The paper shows that incorporating cell size parameters improves deconvolution of brain RNA-seq data, but using external cell size estimates can introduce bias.

The paper identifies widespread genetic influences on DNA methylation in the human brain and links schizophrenia GWAS variants to epigenetic changes.

This study identifies DNA methylation differences in the nucleus accumbens of smokers versus nonsmokers, revealing both shared and tissue-specific CpGs associated with smoking.

The paper uses hiPSC transcriptomics to study neuronal differentiation and maturation across multiple conditions and develops a tool to estimate neuronal maturity.

The paper identifies regional differences in gene expression and regulation in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia using RNA-seq data from 900 samples.

The paper identifies differentially methylated DNA sites and associated genes in Alzheimer’s disease across multiple brain regions, linking them to gene expression and biological processes.

This study identifies gene expression changes in the prenatal human cortex due to maternal smoking and links them to neuropsychiatric disorder risk genes.