Author

Kenneth Gerard Nepple

University of IowaORCID 0000-0001-8100-4190Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

David Henry LumiD· 2 shared Eric A. SingeriD· 2 shared Jennifer M. KingiD· 2 shared Laura Graham· 2 shared Michelle L. ChurchmaniD· 2 shared Neeraj AgarwaliD· 2 shared Paul Vincent ViscuseiD· 2 shared Saum Ghodoussipour· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

David Henry LumORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 6, 2026

SWI/SNF Alterations Define a Chromatin-Dependent Subtype of Urothelial Carcinoma

Bing Feng, Kaniz Fatema, David Austin Nix…·Sumati V. Gupta

This paper identifies a chromatin-altered subtype of urothelial carcinoma defined by SWI/SNF alterations, showing it is sensitive to HDAC inhibition and immunotherapy.

DOI 10.64898/2026.08.05.743022

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 25, 2026

Defining biologically directed therapy target signatures in urothelial carcinoma: A transcriptomic framework for precision therapy

Edwin Lin, Feng Bing-Jian, Kaniz Fatema…·Sumati Gupta

This paper identifies biologically distinct transcriptomic and proteomic patterns of ADC and immunotherapy targets in urothelial carcinoma, linking them to histologic and molecular subtypes for precision therapy.

DOI 10.64898/2026.06.24.734314

humanbulk RNA-seq

𝕏 PostBluesky