David Austin Nix

This paper identifies a chromatin-altered subtype of urothelial carcinoma defined by SWI/SNF alterations, showing it is sensitive to HDAC inhibition and immunotherapy.

This study identifies TEAD inhibition as a therapeutic target in meningioma and shows that combining MEK and mTOR inhibition overcomes resistance in resistant lines.

This study identifies obesity-driven inflammatory and metabolic transcriptomic signatures in mouse and human colon tumors through integrated transcriptomic analyses.

This study identifies ZAG/AZGP1 as a secreted factor from triple-negative breast cancer cells that promotes fibrosis in the tumor microenvironment and is linked to poor patient prognosis.